Table 1

First symptoms of Huntington’s disease

Symptom	No of patients^1-150	% all observed symptoms^1-151
Chorea	877	28
Trouble walking	262	9
Unsteadiness/imbalance	260	8
Difficult to get along with	167	5
Depression	165	5
Clumsiness	154	5
Speech difficulty	149	5
Memory loss	93	3
Trouble holding an object	62	2
Lack of motivation	53	2
Suspicions/paranoia	48	2
Intellectual decline	44	1
Changes in sleep	30	1
Hallucinations	23	1
Weight loss	20	0.6
Sexual problems	7	0.2
Sadness	7	0.2
Other mental	363	12
Other physical	297	10

↵1-150 The number of patients is reported from a total of 1901 patients with initial symptom information.
↵1-151 The per cent of all observed symptoms from a total of 3086 reported symptoms. Patients could report up to three initial symptoms.