1H-MRS findings

n=6/6PML
(mean (SD))
Control subjects
(mean (SD))
p Value
STEAM-20:
 Lipids (0.9)/Cr1.61 (0.42)0.23 (0.40)0.01
 Lactate+lipids / Cr1.31 (0.38)0(*)
 NAA / Cr0.78 (0.21)1.37 (0.10)0.01
 Cho / Cr1.23 (0.19)0.92 (0.11)0.01
 mI / Cr0.76 (0.12)0.65 (0.07)NS
PRESS-135:
 Lactate/ Cr0.39 (0.17)0(*)
 NAA/Cr0.77 (0.09)2.01 (0.22)0.01
 Cho/Cr1.53 (0.26)1.17 (0.22)0.04
  • Metabolite ratios calculated from the STEAM-20 and PRESS-135 spectra of parieto-occipital white matter of control subjects and patients with PML lesions. Values are expressed as mean (SD).

  • (*) Differences were qualitative.