Table 2

Summary of symptoms and findings in our patients with Hashimoto’s encephalitis

Case	1	2	3	4	5	6	7
Age	58	54	44	53	73	80	86
Sex	F	F	F	F	F	F	F
Symptoms:
Dementia	+	+	+	+	+	+	+
Cerebellar ataxia	+	+	+	+	+	+	+
Myoclonus	+	+	+	+	+	+	+
Extrapyramidal signs				+
Pyramidal signs	+						+
Hallucinations	+			+	+
Reduced consciousness	+	+		+	+	+
Epileptic seizures	+	+
Psychosis		+	+		+
Stroke-like episodes				+	+	+	+
Apathy	+	+	+		+		+
Laboratory findings:^2-150
Thyroid parameters	Euthyroid	Hyperthyroid	Euthyroid	Euthyroid	Euthyroid	Euthyroid	Euthyroid
TSH	Increased	Reduced	Normal	Normal	Normal	Normal	Increased
Thyroglobin antibodies	232 U/ml	147 U/ml	Normal	171 U/ml	Normal	^2-151	Normal
Microsomal antibodies	Normal	Normal	548 U/ml	Normal	205 U/ml	^2-151	1602 U/ml
CSF findings:
Leucocyte density	13 leuc/μl	21 leuc/μl	Normal	5 leuc/μl	Normal	Normal	Normal
Protein in CSF	Increased	Increased	Increased	Increased	Normal	Normal	Increased
CSF/serum albumin ratio	Increased	Increased	Increased	Increased	Normal	Normal	Increased
Brain atrophy:	No	No	Yes	No	Yes	No	Yes

↵2-150 The following thyroid parameters were determined: triiodothyronine, free L-thyroxin, thyroid-stimulating hormone (TSH), thyroglobulin antibodies (normal range <60 U/ml), microsomal antibodies (=autoantibodies to thyroid peroxidase, normal range <60 U/ml).
↵2-151 In this case Hashimoto’s encephalitis was diagnosed because of neurological symptoms, excluding other diseases and improvement after corticoid therapy.