Study of the independent effect of sex and educational attainment on dementia and Alzheimer’s disease. PAQUID 1989–95. n=2881
| Dementia | Alzheimer’s disease | ||||||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | p Value | Log likelihood | HR (95% CI) | p Value | Log likelihood | ||
| Model 1 | −1106.78 | −796.87 | |||||
| Sex3-150 (female v male) | 0.396 (0.09–0.90) | 0.033 | 0.395 (0.06–1.17) | 0.081 | |||
| Age by sex | 1.072 (1.014–1.132) | 0.013 | 1.076 (1.007–1.149) | 0.029 | |||
| Model 2 | −1101.83 | −794.72 | |||||
| Education | 1.83 (1.37–2.44) | <0.001 | 1.81 (1.30–2.53) | <0.001 | |||
| Model 3 | −1098.66 | −791.22 | |||||
| Sex3-150 (femalev male) | 0.376 (0.082–0.857) | 0.027 | 0.378 (0.061–1.125) | 0.072 | |||
| Age by sex | 1.072 (1.014–1.132) | 0.013 | 1.076 (1.007–1.149) | 0.030 | |||
| Education | 1.82 (1.36–2.42) | <0.001 | 1.78 (1.27–2.45) | <0.001 | |||
↵3-150 The hazard ratio is given for a woman aged 65. The hazard ratio of developing Alzheimer’s disease for a women aged 85 years is : 0.395×(1.076)(85–65) = 1.71