Log rank (Mantel-Cox) test for time to stop topiramate
| Variable | χ2 | Df | p Value |
|---|---|---|---|
| Sex | 0.017 | 1 | 0.896 |
| Learning disability | 1.30 | 1 | 0.254 |
| History of depression | 0.44 | 1 | 0.508 |
| History of behavioural difficulties | 0.646 | 1 | 0.422 |
| Epilepsy classification2-150 | 0.61 | 1 | 0.44 |
| Partial / generalised2-151 | 0.07 | 1 | 0.793 |
| Generalised tonic clonic seizures2-152 | 0.32 | 1 | 0.570 |
| Previous drug therapy2-153 | 0.62 | 1 | 0.733 |
| Escalation regime2-154 | 4.06 | 1 | 0.044 |
| Add-on / substitution | 3.88 | 1 | 0.049 |
↵2-150 Cryptogenic partial; symptomatic partial; idiopathic generalised; symptomatic generalised.
↵2-151 Partial (cryptogenic and symptomatic) vgeneralised (idiopathic and symptomatic).
↵2-152 Generalised tonic-clonic seizures v other types.
↵2-153 One, two, or three drugs.
↵2-154 Standard (50 mg/day, increasing by 50 mg/day at 2 weekly intervals to 100mg twice daily), faster or slower.