Patient | Latency to M tibialis anterior (ms) R/L | C(MEP) amplitude (mV) | Central latency (ms) |
---|---|---|---|
II–2 | 42.94-150/42.74-150 | 2.0/3.5 | 16.64-150/15.0 |
III–1 | 36.0/36.2 | 2/1 | 13.7/13.5 |
III–2 | 41.14-150/40.94-150 | 2.3/2.9 | NC/NC |
III–3 | 39.6/40.44-150 | 1.6/2.7 | 13.7/17.44-150 |
III–4 | 38.04-150/36.84-150 | 4.8/4.0 | NC/NC |
↵4-150 Pathological values. NC=could not be calculated because the F-wave latency could not be measured.
Since neither F-wave latencies nor lumbar potentials could be determined in III-2 and III-4, no central latency could be calculated in these patients. However, the abnormal long latency to the M. tibialis anterior in these patients with only moderate peripheral motor NCV slowing suggests strongly a central involvement. Most interestingly, although severly affected, a pathological central latency could be determined in index patient III-3, which clearly demonstrates central motor involvement in this patient.