Table 2

Apolipoprotein E allele frequencies among presenilin-1 genotypes

Presenilin-1 genotype2-150Allele2-151
1/11/22/212
Younger control:
ε22  (0.05)3  (0.05)1  (0.06)0.580.42
 ε333 (0.79)48 (0.80)14 (0.88)0.600.40
 ε47 (0.17)9 (0.15)1 (0.06)0.680.32
Early onset AD:
ε24 (0.10)2 (0.03)1 (0.06)0.610.39
 ε325 (0.60)34 (0.57)10 (0.63)0.600.40
 ε413 (0.31)24 (0.40)5 (0.31)0.610.39
Elderly control:
ε28 (0.07)5 (0.03)3 (0.08)0.660.34
 ε3101 (0.86)135 (0.84)33 (0.87)0.630.37
 ε49 (0.08)20 (0.13)2 (0.05)0.610.39
Late onset AD:
ε22 (0.02)2 (0.01)1 (0.02)0.600.40
 ε381 (0.66)103 (0.68)26 (062)0.630.37
 ε439 (0.32)47 (0.31)15 (0.36)0.620.38

  • ↵2-150 Number of alleles (frequency).

  • ↵2-151 Frequency. AD=Alzheimer’s disease.