Correlations between structural volume changes (normalised volume differences between patients and controls) and clinical data (Spearman’s rank correlation coefficients)
| Upper cervical cord | Cerebral white matter | |
|---|---|---|
| EDSS | −0.37 (p=0.023)5-150 | −0.37 (p=0.018)5-150 |
| AI | −0.33 (p=0.045)5-150 | −0.35 (p=0.027)5-150 |
| SNRS | +0.49 (p=0.002)** | +0.43 (p=0.007)5-150 |
| Disease duration | −0.38 (p=0.019)5-150 | −0.45 (p=0.004)** |
| Exacerbation rate (in last 2 y) | +0.34 (p=0.040)5-150 | +0.33 (p=0.036)5-150 |
↵5-150 Trend (0.005<p<0.05); **Significant after Bonferroni (p<0.005).