(3-151) | Myasthenia gravis (total) ( n=25) | Myasthenia gravis (with dysphagia) (n=15) | Myasthenia gravis(without dysphagia) (n=10) | Normal subjects (n=17) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3 ml water | Dry swallowing | 3 ml water | Dry swallowing | 3 ml water | Dry swallowing | 3 ml water | Dry swallowing | ||||||||
0–2 Interval (laryngeal relocation time) | 713 (178) p<0.01 | 672 (193) p<0.01 | 785 (175) p<0.001 | 677 (168) p<0.01 | 620 (139) NS | 537 (170) NS | 571 (85) | 534 (108) | |||||||
Swallowing variability (jitter) | 120 (81) p<0.05 | 159 (111) p<0.05 | 147 (86) p<0.05 | 197 (110) p<0.01 | 85 (60) NS | 88 (71) NS | 82 (39) | 105 (46) | |||||||
A-C interval (SM-EMG duration) | 1136 (257) p<0.001 | 1273 (360) p<0.001 | 1237 (288) p<0.001 | 1420 (363) p<0.001 | 1004 (130) p<0.01 | 1052 (227) p<0.05 | 863 (89) | 896 (153) | |||||||
SM-EMG amp | 51 (34) NS | 56 (37) p<0.05 | 49 (28) p<0.05 | 48 (28) p<0.01 | 53 (41) NS | 68 (46) NS | 62 (27) | 82 (28) | |||||||
A-0 interval3-152 | 328 (161) NS | 382 (227) NS | 323 (160) NS | 36 7 (202) NS | 334 (170) NS | 404 (273) NS | 286 (125) | 312 (178) |
↵3-150 Statistical comparisons between the patient groups have not been included in this table (see text).
↵3-151 Swallowing variables except SM-EMG amp (μV) are in ms and the values are shown as mean (SD).
↵3-152 A-O interval denotes the time interval at the onset of SM-EMG (A) and the onset of the laryngeal upward movements (0). This value is closely related to the time until triggering of the swallowing reflex.10 12