Table 1

Morphometric data in the cerebellar cortex and inferior olivary nucleus

		Purkinje cells (cells/mm)			Granule cells (×10⁶cells/mm³)		Inferior olivary neurons (×10² cells/mm³)
		Superior vermis^1-151	Superior hemisphere^1-151		Tonsil	Superior vermis^1-151	Inferior olivary neurons (×10² cells/mm³)	Superior hemisphere^1-151	Tonsil
Control (n=5)	5.64	5.88	5.93	2.24	2.21	2.16	150.83
Patient 1	0.42^**	4.74^*	4.52^*	1.67^*	1.86^*	2.12	135.47
Patient 2	0.37^**	5.12	5.27	1.02^*	2.03	2.15	129.95
Patient 3	0.31^**	0.97^**	2.53^**	0.77^*	1.50^*	1.84	76.26^*

Patients 1 to 3 correspond to patients UT1-IV-5, UT1-V-7, and UT2-III-1, respectively (see text).
↵1-151 The superior vermis and superior hemisphere designate the culmen and simple lobule, respectively.
The degree of neuronal loss was evaluated as follows; mild or minimal (no symbols): within 15% reduction compared with a normal control; moderate ^*; between 15 and 50% reduction; severe ^**: more than 50% reduction.
Note that the Purkinje cells are consistently and predominantly affected.