Univariate relation between the presence of possible explanatory factors and the severity of carotid disease
| Variable | Severity of stenosis (n (%)) | Total | OR (p Value) | ||||
|---|---|---|---|---|---|---|---|
| <70% | 70-99% | 100% | |||||
| Ipsilateral carotid bruit | 54 (9) | 54 (56) | 11 (23) | 119 (16) | 11.2 (<0.001) | ||
| Contralateral carotid bruit | 51 (9) | 37 (39) | 11 (23) | 99 (14) | 5.7 (<0.001) | ||
| Cortical event | 307 (53) | 55 (57) | 31 (66) | 393 (54) | 1.2 (0.5) | ||
| Lacunar event | 195 (33) | 15 (16) | 5 (11) | 215 (30) | 0.4 (<0.001) | ||
| Previous TIA | 70 (12) | 24 (25) | 9 (19) | 103 (14) | 2.3 (0.001) | ||
| 1-150Peripheral vascular disease | 83 (14) | 27 (28) | 20 (43) | 130 (18) | 2.0 (0.005) | ||
| 1-151Ischaemic heart disease | 136 (23) | 33 (34) | 20 (43) | 189 (26) | 1.6 (0.05) | ||
| 1-152Hypertension | 226 (39) | 47 (49) | 25 (53) | 298 (41) | 1.4 (0.09) | ||
| Diabetes mellitus | 52 (9) | 15 (16) | 6 (13) | 73 (10) | 1.8 (0.05) | ||
| Current smoker (cigarette or other) | 209 (36) | 48 (50) | 21 (45) | 278 (38) | 1.7 (0.01) | ||
| Male sex | 321 (55) | 56 (58) | 31 (66) | 408 (56) | 1.1 (0.7) | ||
| Age>65 | 336 (58) | 65 (68) | 28 (60) | 429 (59) | 1.5 (0.07) | ||
| Total | 583 | 96 | 47 | 726 | |||
The row totals are the number of patients who have each of the possible factors, and the column totals are the number of patients with each of the categories of stenosis. Some patients had more than one risk factor, so the number of risk factors in each column do not add up to the column total. The % are of column totals. TIA=transient ischaemic attack.
p Values are from χ2 tests comparing those with 70-99% stenosis to all other patients (<70% stenosis and 100% stenosis combined) for patients with and without each possible explanatory factor.
↵1-150 Peripheral vascular disease was defined as the absence of both foot pulses or femoral bruits, a history of intermittent claudication, or a history of peripheral vascular surgery.
↵1-151 Ischaemic heart disease included either angina pectoris or previous myocardial infarction.
↵1-152 Hypertension included a history of hypertension or treatment at any time.
Diabetes mellitus was defined as history of diabetes mellitus at the time of assessment, on diet, oral hypoglycaemic drugs or insulin.