1H MRS findings in patients with Parkinson’s disease and control subjects
| Region | Parkinson’s disease | Control subjects |
|---|---|---|
| NAA/Cr | ||
| Right and left TP averaged | 1.78 (0.30)2-150 | 2.20 (0.38) |
| Contralateral TP | 1.61 (0.30)** | |
| Ipsilateral TP | 1.95 (0.53) | |
| Right TP (contralateral hemisphere in 7 patients) | 1.81 (0.48) | 2.24 (0.56) |
| Left TP (contralateral hemisphere in 10 patients) | 1.75 (0.44)2-150 | 2.17 (0.34) |
| Occipital | 2.38 (1.10) | 2.54 (1.07) |
| NAA/Cho | ||
| Right and left TP averaged | 3.03 (0.65) | 2.74 (0.56) |
| Contralateral TP | 3.08 (1.40) | |
| Ipsilateral TP | 2.89 (0.80) | |
| Right TP | 3.08 (0.84) | 2.93 (0.64) |
| Left TP | 2.89 (1.38) | 2.56 (0.64) |
| Occipital | 4.81 (2.44) | 3.79 (1.12) |
| Cho/Cr | ||
| Right and left TP averaged | 0.69 (0.20) | 0.82 (0.22) |
| Contralateral TP | 0.63 (0.25) | |
| Ipsilateral TP | 0.76 (0.32) | |
| Right TP | 0.66 (0.24) | 0.76 (0.22) |
| Left TP | 0.74 (0.35) | 0.83 (0.21) |
| Occipital | 0.64 (0.44) | 0.73 (0.45) |
Results are given as mean (SD). TP=Temporoparietal; contralateral=contralateral to worst clinically affected limbs in patients with Parkinson’s disease; ipsilateral=ipsilateral to worst clinically affected limbs in patients. All right, left, contralateral, and ipsilateral TP values for the patients were compared with the average of right and left TP values for the controls.
↵2-150 p<0.05; **p<0.01 (Bonferroni correction) between controls and patients.