Variable | Patient 1 | Patient 2 |
Antibody titres: | ||
IgM GM1 | 1:64000 | 1:4000 |
IgG GM1 | — | — |
IgM asialo-GM1 | 1:32000 | 1:8000 |
IgG asialo-GM1 | — | — |
IgM GD1a | — | — |
IgG GD1a | — | — |
IgM GD1b | 1:500 | 1:32000 |
IgG GD1b | — | — |
IgM GT1b | — | 1:2000 |
IgG GT1b | — | — |
IgM GQ1b | — | — |
IgG GQ1b | — | — |
IgM sulfatide | — | — |
IgG sulfatide | — | — |
Nerve conduction studies: | ||
Right median nerve: | ||
DL (ms)/NCV1/NCV2 (m/s) | 4.5/48/56 | 4.6/32/65 |
F wave latency (ms) | 33.0 | 43.6 |
Motor conduction block | + | + |
SNAP | Absent | Absent |
Right ulnar nerve: | ||
DL (ms)/NCV1/NCV2(m/s) | 2.6/56/50 | 3.0/35/45 |
F wave latency (ms) | 32.5 | 43.9 |
Motor conduction block | + | − |
SNAP | Absent | Absent |
Right peroneal nerve: | ||
DL (ms)/NCV1/NCV2(m/s) | 6.6/42/39 | 5.2/33/31 |
F wave latency (ms) | 86.9 | 62.5 |
Motor conduction block | + | + |
SNAP | Absent | Absent |
Antibody titres presented are those before treatment (baseline).
SNAP=sensory nerve action potential; DL=distal latency; NCV=motor nerve conduction velocity in the following segments: median nerve: wrist-elbow (NCV1, normal >50m/s), elbow-axilla (NCV2, normal >56m/s); ulnar nerve: wrist-elbow (NCV1, normal >50m/s), elbow-axilla (NCV2, normal >55m/s); peroneal nerve: ankle-fibula neck (NCV1, normal >42m/s), fibula neck-popliteal fossa (NCV2, normal >41m/s).