Table 3

MSQOL mean scores by expanded disability status scale (EDSS) scores in a survey of people with relapsing-remitting multiple sclerosis

ScaleEDSS scorep Value3-151
0–33-150
Mean (SD)
3.5–5.53-150 Mean (SD)6+3-150
Mean (SD)
Physical function (PF)54.2 (29.8)25.9 (20.9)12.6 (12.0)<0.0001
Role physical (RP)44.8 (43.0)19.2 (29.1)15.8 (37.5)0.01
Role emotional (RE)67.8 (44.0)55.9 (46.7)45.6 (48.7)0.30
Bodily pain (BP)67.7 (23.8)65.2 (26.1)65.2 (28.3)0.92
Mental health (MH)71.6 (17.5)67.1 (19.5)59.8 (26.8)0.27
Energy/vitality (VT)39.3 (17.5)36.6 (19.7)35.3 (21.1)0.84
Health distress (HD)64.3 (24.7)56.3 (29.9)39.3 (28.6)0.01
Social function (SF)65.7 (26.2)56.9 (23.1)41.7 (23.3)0.005
Cognitive function (CF)71.3 (25.9)67.9 (23.7)54.3 (32.5)0.14
Sexual function (SX)69.8 (31.6)48.3 (27.5)42.9 (37.2)0.007
General health (GH)42.1 (21.8)37.9 (21.5)38.6 (25.3)0.75
Overall quality of life (QOL)79.3 (85.1)53.6 (19.1)49.9 (22.9)0.04
Change in health (TRANS)48.3 (27.0)39.8 (20.9)34.5 (24.3)0.25
Physical health composite score45.4 (18.2)36.1 (15.7)31.2 (15.9)0.03
Mental health composite score67.5 (24.2)59.3 (22.9)49.9 (24.5)0.05
  • 3-150 For each scale, a few patients did not complete sufficient items to permit computation. Bases on which scale scores were calculated range from 26 to 30 for patients with EDSS of 0–3; from 29 to 32 for patients with EDSS of 3.5–5.5; from 19 to 21 for patients with EDSS of 6 and over.

  • 3-151 Kruskal-Wallis 1 way ANOVA.