|
Standard care
|
Drug therapy
|
Difference
|
5 Year model with no effect on progression
|
Relapses | 5.23 | 3.71 | 1.52 |
Undiscounted costs: | | | |
Relapses | £11000 | £7800 | £3200 |
IFβ-1b | £0 | £52500 | £52500 |
Total costs | £11000 | £60300 | £49300 |
Cost per relapse avoided | | | £32400 |
Discounted costs: | | | |
Relapse | £10000 | £7100 | £2900 |
IFβ-1b | £0 | £46600 | £46600 |
Total cost | £10000 | £53600 | £43600 |
Cost per relapse avoided | | | £28700 |
QALY gain: | | | |
Undiscounted | −0.204 | −0.145 | 0.059 |
Discounted | −0.184 | −0.130 | 0.054 |
Cost per QALY gained: | | | |
Undiscounted | | | £831400 |
Costs only discounted | | | £736200 |
Costs and QALYs discounted | | | £809900 |
5 Year model with effect on progression
|
Costs | £15200 | £58600 | £43400 |
QALY gain | 3.08 | 3.21 | 0.13 |
Cost per QALY gained | | | £328300 |
10 Year model with effect on progression: base case
|
Costs | £29900 | £104700 | £74800 |
QALY gain | 5.32 | 5.65 | 0.33 |
Cost per QALY gained | | | £228300 |
10 Year model with effect on progression: best case
|
Costs | £29900 | £102200 | £72300 |
QALY gain | 5.25 | 6.23 | 0.98 |
Cost per QALY gained | | | £74500 |
10 Year model with effect on progression - worst case
|
Costs | £29900 | £105400 | £75500 |
QALY gain | 5.32 | 5.45 | 0.13 |
Cost per QALY gained
| | |
£604600
|