Table 4

Baseline score distributions in instruments measuring a range of health related constructs

Measurement instrument
(scale range)
Total sample (n=149) Mild
(n=47)
Moderate (n=51) Severe (n=51)
EDSS (0–10):
 Sample range1.0–9.01.0–4.55.0–6.57.0–9.0
 Median6.53.06.58.0
 Mean (SD)5.7 (2.1)2.9 (0.8)6.17.8 (6.5)
 Floor/ceiling effect (%)0/00/00/0 0/0
FIM motor (13–91):
 Sample range13–9174–9143–9013–81
 Mean (SD)69.7 (20.6)87.5 (3.5)75.5 (8.7)47.7 (18.9)
 Floor/ceiling effect (%)1/50/170/02/0
LHS (0–100):
 Sample range35–10048–10043–91.935–93.7
 Mean (SD)69.5 (13.3)79.2 (13.2)68.2 (10.1)61.8 (10.7)
 Floor/ceiling effect (%)0/00/8.50/00/0
GHQ (0–28):
 Sample range0–280–240–230–28
 Mean (SD)6.2 (6.5)5.6 (6.8)4.9 (4.9)8.0 (7.2)
 Floor/ceiling effect (%)1/250/32 0/23.52/19.6
0–10 point global rating scale of QOL:
 Sample range0–10023.3–1005–850–81.6
 Mean (SD)55.4 (19.6)64.0 (19.9)55.9 (15.6)46.6 (19.6)
 Floor/ceiling effect (%)1/10/20/04/0
  • Mild=EDSS 0–4.5; Moderate=EDSS 5.0–6.5; Severe=EDSS 7.0–9.5.