Patients' description
| No | Sex | Age of onset | Preceding psychiatric history | Family history | Previous history of substance misuse | Motor complications | Mood disorder | Behavioural disorder | Interpersonal relationships | Employment history |
Max daily levodopa dose | Max daily oral dopamine agonist dose | Max daily apopmorphine dose | Comments |
| 1 | M | 36 | Depression | Depression | Ex-smoker, moderate alcohol consumption | Dyskinesias, motor blocks, on-offs unpredictable dose effect | Cyclothymic | Hypersexuality | Long history of marital difficulties | Early retirement due to PD | 3200 mg | Trials of bromocriptine (max daily dose 15 mg) | 170 mg | Admitted several times with acute psychosis related to apomorphine abuse |
| 2 | F | 39 | Depression, panic attacks as a teenager | Nil | Nil | Dyskinesias, motor blocks, on-offs | Depression and hypomanic episodes | Anxiety, panic attacks | Nil | Early retirement | 1875 mg | Pergolide 1.5 mg | 138 mg | Admitted with hypomania and a paranoid delusional disorder |
| 3 | M | 40 | Mild pre-morbid depression | Nil | Nil | Dyskinesias, rapid on-offs, unpredictable dose effect | Depression | Exhibitionism | Family difficulties | Early retirement | 2125 mg | nil | 110 mg | Tried continuous apomorphine infusion but missed the “hit” of the intermittent injection. Despite increasing dyskinesias felt under medicated. |
| 4 | M | 42 | Nil | Nil | Nil | Motor fluctuations, dyskinesias, on-offs unpredictable dose effect | Manic psychosis | Disinhibited, hypersexualty | Divorced due to behavioural disorder | Early retirement | 5500 mg | Bromocriptine 70 mg | 75 mg | Preferred intermittent apomorphine injections to continuous subcutaneous infusion |