Electron microscopic morphometric evaluation of the transverse profiles of secretory coils in the skin and nerve terminals and unmyelinated axons around secretory coils

Controls1-151 Patient1-152
Perimeter of transverse profile (μm/profile)173  (55)122  (88–156)
Area of transverse profile (μm2/profile)2017 (1000)990 (445–1445)
Nerve terminals (n)1-150 9.1 (4.8)1.1 (0–2.4)
Unmyelinated axons (n)1-150 12.7 (6.2)1.8 (0–3.7)
  • 1-151 Mean (SD) of six control subjects in whom 14–38 transverse profiles of secretory coils in each individual were morphometrically evaluated.

  • 1-152 Mean of 38 transverse profiles of secretory coils. Minimum–maximum values are shown in parentheses.

  • 1-150 Number/100 μm of perimeter of transverse profiles.