Table 5

Summary of studies investigating the relation between the OCSP clinical classification of ischaemic stroke and the site of any lesion on CT or MRI

AuthorNumber of ischaemic strokes Recent infarcts on CT or MRI (%)Proportion of infarcts appropriate to each of the syndromes(%)Comments
TAC1PAC1LAC1POC1Overall
Anderson et al19944  248162 (65)46/58 (79) 25/44 (57) 30/48 (62) 12/20 (60)113/162 (70)Community first ever strokes, retrospectively classified
Lindgrenet al 19945 (and personal communication) 179110 (61)35/39 (90) 21/37 (57) 13/22 (59) 12/12 (100) 81/110 (74)First ever stroke. Previously unpublished data
Wardlaw et al 19966  108 91(84)30/33 (91) 30/36 (83) 12/14 (86)  8/8 (100) 80/91 (88)Hospital series. Included previous non-disabling strokes
Mead et al 19967  195158 (81)41/46 (89) 48/57 (84) 25/37 (68) 16/18 (89)130/158 (82)Hospital series. Only half of CT reports of 378 patients with ischaemic stroke were available
Al-Buhairi et al19988  378239 (63)40/49 (82) 79/82 (94) 65/66 (98) 32/32 (100)216/228 (95)Hospitals series of acute ischaemic strokes. Included previous strokes
Current study1012 655 (65)69/87 (79)213/298 (71)104/144 (73)105/126 (83)492/655 (76)Validity similar for those with and without previous strokes
  • “Appropriate infarcts” are defined in different ways.

  • For Anderson et al, Meadet al, and Lindgren et al, 4 5 7 any cortical infarct or large subcortical infarct is defined as “appropriate” for both TACIs and PACIs, small subcortical for LACIs and posterior circulation for POCIs.

  • Wardlaw et al 6 and the current study used stricter definitions of “appropriate infarcts”: large cortical, medium cortical, and large subcortical were appropriate for TACIs; and medium cortical, small cortical, and large subcortical were appropriate for PACIs.

  • Al-Buhairi et al 8 classified complete MCA territory infarction, ACA territory infarction as appropriate for TACIs, partial MCA infarcts, and subcortical infarcts as appropriate for PACIs.