Comparison of the 15 patients of the present study (group I) with the five patients who dropped out 2 years postpallidotomy (group II)
|
Group I (n=15) Mean (SD) |
Group II (n=5) Mean (SD) | |
| Age at surgery (y) | 64.7 (7.4) | 49.6 (12.0) |
| Hoen and Yahr stage: | ||
| Off state | 3.2 (0.8) | 3.3 (0.7) |
| On state | 2.4 (0.5) | 2.5 (0.5) |
| Duration of disease (y) | 14.5 (9.0) | 14.0 (2.7) |
| Duration of treatment (y) | 11.9 (6.3) | 13.4 (2.9) |
| Duration of fluctuations (y) | 7.4 (5.1) | 7.4 (2.5) |
| Duration of dyskinesias (y) | 6.8 (4.6) | 5.8 (5.7) |
| Dose of levodopa/carbidopa (mg) | 1000 (395) | 1340 (450) |
| Dose of dopamine agonist (mg) | 26.0 (21.5) | 36.0 (18.5) |
| Improvement in CL dyskinesia at 2 years (score) | 2.6 (2.1) | 2.7 (1.4) |
| Improvement in CL off state tremor at 2 years (score) | 1.88 (1.8) | 1.5 (1.8) |
CL=Contralateral; improvement=(mean score prepallidotomy)−(mean score at 2 years) (see text). Group I versus group II: p=0.032 for age at surgery; rest of the p values are not significant.