Table 2

MRI findings in apoE genotype subgroups

All (n=83) ε2/ε3 (n=11) ε3/ε3 (n=49) ε3/ε4 (n=19)
T2 lesion load (cm3)11.6 (10.7) [8.7]13.3 (9.5) [14.4]9.4 (9.2) [5.6]16.0 (14.0) [11.3]
T1 lesion load (cm3)1.6 (3.0) [0.4]1.6 (2.4) [0.6]1.2 (3.0) [0.1]2.6 (3.3) [1.1]2-150
“Black hole” ratio (%)9.6 (12.5) [5.8]7.4 (9.3) [6.2]8.4 (13.3) [4.0]14.3 (11.9) [12.4]2-150
Active scans (number)1831312-151

  • Data are given as mean (SD)[median].

  • ↵2-150 ε3/ε4 v ε3/ε3, p<0.02 (Mann-Whitney U test).

  • ↵2-151 ε3/ε4 v ε3/ε3, p<0.05 (χ2 test).