Comparison of hypothyroid and hyperthyroid patients
| Hypothyroidism (n=24) | Hyperthyroidism (n=21) | p Value | |
| Age (y) (mean (SD)) | 47.8 (13) | 43.2 (13) | NS |
| Height (cm) (mean (SD)) | 165.1 (5.1) | 167.5 (8.2) | NS |
| Duration (months) (mean (SD)) | 20.8 (15.5) | 7.3 (4.3) | 0.006 |
| BMI at entry (mean (SD)) | 28.1 (3.7) | 23.9 (2.8) | <0.005 |
| BMI after therapy (mean (SD)) | 27.5 (3.3) | 26.2 (2.9) | NS |
| Symptoms (n (%)): | |||
| Weakness | 13 (54) | 14 (67) | NS |
| Cramps | 10 (42) | 2 (10) | <0.05 |
| Duration (months) | 19.9 (14.7) | 4.4 (2.5) | <0.005 |
| Sensory symptoms | 7 (29) | 3 (14) | NS |
| Signs (n (%)): | |||
| Paresis of muscle(s): | 9 (38) | 13 (62) | 0.1 |
| Tremor: | 0 (0) | 16 (76) | <0.001 |
| Ankle jerk >+1 | 1 (4) | 9 (43) | <0.01 |
| Ankle jerk <0 | 16 (67) | 4 (19) | <0.005 |
| MRC sum 1st | 147.9 | 141.8 | <0.01 |
| MRC sum 3rd | 149.6 | 150 | NS |
| Mean SSS 1st | 43.1 | 45.1 | NS |
| Mean SSS 3rd | 45.8 | 46.8 | NS |
| Resolution of muscle symptoms (months) (mean (SD)) | 6.9 (4.0) | 3.6 (2.3) | <0.05 |
BMI=body mass index; MRC sum 1st and final=MRC sum score at initiation (1st) and after 1 year of therapy (final); Mean SSS 1st and final=mean sensory sum score at initiation (1st) and after 1 year of therapy (final); NS=not significant.