Table 3

Test scores on the cognitive measures of the two patient groups in the two sessions

Cognitive testsnTopiramate groupComparison group
Session one mean (SD)On TPM Session two mean (SD)Session one mean (SD)Session two
mean (SD)
Verbal IQ1893.5  (9.8)81.0  (11.2)91.2  (8.7)93.6  (10.0)3-165
 Digit span189.3 (3.0)5.6 (3.3)9.4 (3.0)9.5 (1.8)3-160
 Vocabulary187.9 (7.1)7.0 (2.4)7.9 (2.4)8.3 (2.6)
 Arithmetic188.8 (2.9)5.8 (2.3)8.9 (2.9)8.8 (2.5)3-165
 Similarities189.1 (1.9)7.2 (2.3)9.1 (1.9)9.3 (2.5)
Performance IQ1898.7 (12.4)86.7 (16.7)95.4 (14.6)97.8 (16.0)3-160
 Story recall:
  Immediate1721.9 (12.5)14.7 (8.7)29.6 (12.4)30.5 (10.9)3-150
  % Retained1769.2 (22.8)49.6 (34.1)92.5 (12.0)91.0 (14.8)3-160
 List learning:
  Lists 1–51844.2 (10.1)34.1 (14.2)45.0 (8.8)48.3 (9.5)3-165
  List 6189.1 (4.3)6.1 (3.3)9.8 (2.6)10.4 (2.6)3-160
  List B184.8 (2.1)4.8 (1.9)4.9 (1.6)5.2 (2.5)
Graded naming test1815.2 (6.8)13.6 (7.5)16.7 (7.0)16.2 (7.0)
De Renzi token test1513.8 (1.3)10.6 (3.9)14.0 (1.1)14.1 (1.0)3-160
Verbal fluency ‘s’1813.4 (5.5)7.1 (4.5)11.8 (2.7)15.2 (3.4)3-165
 Animals1815.7 (5.8)10.6 (3.9)17.5 (4.7)20.0 (4.6)3-165
Figure recall:
 Immediate1570.6 (18.9)57.2 (21.8)73.2 (16.2)75.5 (18.0)
 % Retained1589.7 (10.9)94.1 (10.7)95.9 (7.7)90.3 (24.9)
Design learning:
 Designs 1–51633.7 (8.8)28.3 (9.2)35.0 (5.6)35.6 (8.5)
 Design 6166.6 (2.4)5.3 (2.9)7.5 (2.3)7.7 (2.3)
 Design B164.1 (2.2)5.0 (2.4)5.7 (1.9)6.3 (2.3)
Fragmented letters1618.5 (1.4)17.6 (2.6)17.9 (1.3)18. (1..5)
  • 3-150 p<0.05;

  • 3-160 p<0.01;

  • 3-165 p<0.001.