Table 4

Test scores of patients before, during and following withdrawal (n=7) or reduction (n=1) of topiramate

Cognitive tests Pre-TPM Mean (SD) On TPM Mean (SD) TPM ↓
Mean (SD)
Digit span8.6  (1.8)6.0  (3.8)8.4  (3.1)4-165
List learning:
 Lists 1–539.9 (6.1)33.5 (13.6)42.6 (7.9)4-160
 List 67.4 (1.9)5.0 (3.2)7.5 (2.5)4-160
Verbal fluency ‘s’8.9 (2.4)6.1 (3.6)10.0 (4.6)4-160
 Animals13.4 (2.8)9.8 (2.9)14.4 (3.6)4-160
  • 4-150 p<0.05;

  • 4-160 p<0.01;

  • 4-165 p<0.001.