Patients' characteristics
| Patients | Age (y) | Sex | Disease duration (y) | Hoehn and Yahr score “off/on” | Dosage of levodopa equivalents (mg/day) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Before surgery | After surgery | Before surgery | After surgery | ||||||||||
| 1 | 40 | M | 15 | 5/4 | 1.5/1 | 1250 | 1100 | ||||||
| 2 | 45 | M | 11 | 5/4 | 1/0 | 1550 | 525 | ||||||
| 3 | 64 | F | 28 | 4/3 | 1.5/1 | 1150 | 300 | ||||||
| 4 | 50 | M | 10 | 3/1.5 | 1/1 | 1550 | 200 | ||||||
| 5 | 54 | M | 17 | 4/2 | 2/1 | 600 | 250 | ||||||
| 6 | 65 | M | 11 | 5/2.5 | 2/1 | 1450 | 450 | ||||||
| 7 | 74 | F | 25 | 3/1 | 1/0 | 350 | 0 | ||||||
| 8 | 46 | F | 15 | 5/3 | 1.5/1 | 1500 | 500 | ||||||
| 9 | 46 | M | 11 | 3/2 | 1/0 | 1250 | 300 | ||||||
| 10 | 61 | F | 8 | 4/2 | 2/1 | 1750 | 475 | ||||||
| Mean (SEM) | 54 (3) | 15 (2) | 4.1 (0.3)/2.5 (0.3) | 1.5(0.1/0.1)1-1506(0.2)1-150 | 1240 (140) | 410 (90)1-150 | |||||||
↵1-150 p<0.01, after surgery under STN stimulationv before surgery.
Levodopa equivalents=dose of levodopa+10×dose of bromocriptine+100×dose of pergolide or lisuride+20×dose of ropinirole+10×dose of apomorphine.