Level and glycosylation of lumbar CSF AChE in various CNS diseases
| Group | Age (y) | Sex (M/F) | % Bound to Con A | Total AChE (nmol/min/ml) |
| Controls (no CNS disease) | 65.8 (3.9) | 5/9 | 1.57 (0.20) | 12.52 (0.81) |
| Probable AD | 65.8 (1.6) | 5/22 | 4.12 (0.89)1-150 | 10.88 (0.97) |
| All CNS diseases (except AD) | 69.8 (3.1) | 16/7 | 2.04 (0.27) | 11.35 (1.07) |
| Cerebrovascular accident | 73.4 (2.2) | 4/1 | 1.98 (0.31) | 12.46 (3.34) |
| Benign intracranial hypertension | 51.0 (5.8) | 1/2 | 1.93 (1.69) | 8.87 (0.94) |
| Normal pressure hydrocephalus | 81.0 (3.8) | 3/3 | 2.45 (0.62) | 12.51 (2.65) |
| Epilepsy | 72.9 (4.4) | 6/1 | 1.97 (0.28) | 10.99 (1.55) |
| Optic neuritis | 43 | 1/0 | 1.30 | 10.65 |
| Multiple sclerosis | 45 | 1/0 | 1.50 | 9.54 |
Values are means (SEM). Controls are cases without CNS disorder (two healthy, five migraine, one breast cancer, five polyneuropathy, one peripheral neuropathy).
↵1-150 Significantly different from all non-AD cases and from no CNS disease controls (Student'st test, p<0.05).