Table 1

Demographic data (mean(SD)) for the 585 study participants with unequivocal DNA results and without manifest Huntington's disease

DemographicPSGCs (n=171)NGCs (n=414)p Value
Age36.4 (8.2)40.6 (10.8)0.0001
Education15.0 (2.6)14.8 (3.0)0.31
Male-female ratio1-150 55/116)126/2880.70
Size of smaller allele19.4 (3.5)18.9 (2.2)1-151 0.05
Size of larger allele42.6 (2.2)20.6 (3.1)0.0001
  • PSGCs=presymptomatic gene carriers; NGCs=non-gene carriers.

  • 1-150 Ratio evaluated using χ2 statistic. All other comparisons performed by t test.

  • 1-151 Average allele size used for the NGC.