Sign/symptom |
CJD patients (%) (n=25) |
AD patients (%) (n=19) |
DLB patients (%) (n=12) |
Dementia | 25 (100) | 19 (100) | 12 (100) |
Myoclonus | 22 (88) | 11 (58) | 9 (75) |
Extrapyramidal signs | 21 (84) | 10 (53) | 11 (92) |
Limb rigidity | 17 (68) | 10 (53) | 11 (92) |
Parkinsonism | 2 (8) | 2 (11) | 7 (58) |
Choreatic/athetoid/ballistic/dystonic signs | 10 (40) | — | — |
Pyramidal signs | 19 (76) | 6 (32) | 2 (17) |
Cerebellar signs | 23 (92) | 7 (37) | — |
Gait or postural ataxia | 20 (80) | 3 (16) | |
Limb ataxia | 15 (60) | 5 (26) | |
Visual disturbances2-150 | 12 (44) | — | — |
Akinetic mutism | 16 (64) | 4 (21) | 1 (8) |
Fluctuations | — | 1 (5) | 7 (58) |
Visual hallucinations | 9 (36) | 2 (11) | 7 (58) |
Recurrent falls | 4 (16) | 6 (32) | 6 (50) |
Neuroleptic hypersensitivity | —2-151 | —2-151 | —2-151 |
Delusions | 3 (12) | 5 (26) | 9 (75) |
↵2-150 Visual disturbances included deterioration of vision (n=2), blurred vision (n=3), visual field restriction (n=4), disturbed perception of structures and colours (n=3), and double vision (n=3).
↵2-151 Neuroleptic medication was received by six AD patients, nine DLB patients, and one CJD patient without notice of hypersensitivity by treating physician.
— Signs not noted.