Baseline laboratory and demographic data in the two treatment groups
|
GKI (n=73) |
Control (n=72) | p Value | |
| Demographic data: | |||
| Sex (male/female) (n) | 36/37 | 0.56 | |
| Median age (y (range)) | 74 (40–97) | 75 (48–93) | 0.37 |
| History of hypertension (n (%)) | 27 (37) | 29 (40) | 0.68 |
| History of ischaemic heart disease (n (%)) | 25 (34) | 16 (22) | 0.19 |
| History of diabetes mellitus (n (%)) | 10 (14) | 10 (14) | 0.97 |
| History of stroke (n (%)) | 8 (11) | 8 (11) | 0.97 |
| Stroke pathology: | |||
| Infarction (n (%)) | 58 (79) | 48 (67) | |
| Haemorrhage (n (%)) | 10 (14) | 13 (18) | |
| Haemorrhagic infarct (n (%)) | 1 (2) | 1 (2) | |
| Unknown (n (%)) | 3 (6) | 10 (14) | 0.62 |
| Clinical stoke subtype: | |||
| TACS (n (%)) | 38 (52) | 35 (48) | |
| PACS (n (%)) | 22 (30) | 25 (34) | |
| LACS (n (%)) | 13 (17) | 7 (10) | |
| POCS (n (%)) | 0 (–) | 5 (7) | 0.07 |
| Clinical and laboratory measurements: | |||
| Median time from stroke to infusion (h (range)) | 13 (3–24) | 11 (2–24) | 0.49 |
| Median time from admission to infusion (h (range)) | 7 (1–23) | 6 (1–22) | 0.64 |
| Mean admission serum cortisol (nmol/l (SD)) | 716 (413) | 641 (344) | 0.30 |
| Mean admission plasma glucose (mmol/l (SD)) | 8.8 (2.3) | 8.6 (2.1) | 0.38 |
| Mean admission plasma sodium (mmol/l (SD)) | 140 (2.9) | 139 (3.7) | 0.06 |
| Mean admission plasma potassium (mmol/l (SD)) | 3.86 (0.40) | 3.82 (0.52) | 0.62 |
| Mean plasma potassium at 24 h (mmol/l (SD)) | 4.13 (0.54) | 3.80 (0.38) | 0.0011-150 |
| Mean admission plasma urea (mmol/l (SD)) | 6.6 (2.1) | 6.4 (2.3) | 0.47 |
| Mean admission plasma creatinine (μmol/l (SD)) | 106 (25) | 105 (25) | 0.62 |
↵1-150 p<0.05; Mann-Whitney U test.
TACS= Total anterior circulation syndrome; PACS=partial anterior circulation syndrome; LACS=lacunar syndrome; POCS=posterior circulation syndrome.