Table 2

Mean values (SD) of NABT-MTR and D̄ histogram derived metrics in patients with LHON and healthy controls

Controls All patients LHON LHON-MS
Mean NABT-MTR (%)40.0  (0.5)39.4  (0.8)39.6  (0.8)38.9  (0.5)
NABT-MTR histogram peak height113.1 (10.5)101.7 (12.7)102.1 (14.3)110.5 (8.6)
NABT-MTR histogram peak location (%)35.3 (1.0)34.8 (1.0)35.2 (1.0)34.0 (0.8)
Average(×10−3mm2s−1)0.91 (0.04)0.96 (0.05)
histogram peak height107.8 (9.5)100.5 (14.6)
histogram peak location (×10−3mm2s−1)0.77 (0.02)0.80 (0.05)
  • See text for further details and statistical analysis.