Table 1

Influence of different factors on the attitude towards childbearing

50 patients with CMT (demyelination and (hereditary or confirmed mutation)) Univariate Logistic regression
1Age (range 17–76 y; mean 47 y)0.35
2Sex (male 19; female 31)0.98
3Affected family members of previous generation (35 patients)0.150.03
4Presence of children (24 patients)0.020.03
51-150 Rankin score (1, 4 patients; 2a, 24 patients; 2b nine paients; 3, 12 paients; 4 one patient)0.010.04
6Deterioration within the past 5 years (27 patients)0.28
7SIP: physical dimension0.18
8Neuropathy related pain or painful muscle cramps (34 patients)0.83
9SIP: psychosocial dimension0.94
10Depression (eight patients)0.13
11Regular use of healthcare institutions (16 patients)0.30
12Use of orthopaedic devices (26 patients)0.09
13Attitude towards childbearing (pro 32 patients; contra 18 patients)
  • 1-150 For calculations values of 2 and 2.5 were used for Rankin grades 2a and 2b. SIP=Sickness impact profile.