Distribution of PON1 and PON2 genotypes and allele frequencies in cases and controls*
| Controls | Neurological controls | Sporadic CJD | Variant CJD | |
| PON1: | ||||
| Codon 54 | ||||
| Genotype | ||||
| LL | 38 (40.9) | 4 (40) | 7 (36.8) | 8 (30.8) |
| LM | 49 (52.7) | 6 (60) | 12 (63.2) | 18 (69.2) |
| MM | 6 (6.4) | — | — | — |
| n | 93 | 10 | 19 | 26 |
| Allele | ||||
| L(Leu) | 0.672 | 0.700 | 0.684 | 0.654 |
| M(Met) | 0.328 | 0.300 | 0.316 | 0.346 |
| Codon 192: | ||||
| Genotype | ||||
| AA | 63 (53.8) | 5 (50) | 10 (52.6) | 14 (53.8) |
| AB | 44 (37.6) | 4 (40) | 8 (42.1 ) | 10 (38.5) |
| BB | 10 (8.5) | 1 (10) | 1 (5.3) | 2 (7.7) |
| n | 117 | 10 | 19 | 26 |
| Allele | ||||
| A(Gln) | 0.726 | 0.700 | 0.737 | 0.731 |
| B(Arg) | 0.274 | 0.300 | 0.263 | 0.269 |
| PON2: | ||||
| Codon 311 | ||||
| Genotype | ||||
| SS | 57 (60) | 5 (50) | 12 (63.2) | 15 (57.7) |
| CS | 33 (34.7) | 4 (40) | 5 (26.3) | 10 (38.5) |
| CC | 5 (5.3) | 1 (10) | 2 (10.5) | 1 (3.8) |
| n | 95 | 10 | 19 | 26 |
| Allele | ||||
| S(Ser) | 0.774 | 0.700 | 0.763 | 0.769 |
| C(Cys) | 0.226 | 0.300 | 0.237 | 0.231 |
Values in parentheses are percentages. All data were analysed using Pearson's χ2 test (significance taken as p<0.05). There were no significant differences between the cases and controls.