Side effects associated with action on different receptors
| Receptor system | Effects |
|---|---|
| Blockade of α1 adrenergic receptors | Postural hypotension, reflex tachycardia |
| Stimulation of serotonin 5-HT1 receptors | Antidepressant, anxiolytic effect, hypophagia |
| Stimulation of serotonin 5-HT2 receptors | Insomnia, sexual dysfunction, agitation |
| Stimulation of serotonin 5-HT3 receptors | Gastrointestinal effects |
| Blockade of M1 muscarine receptors | Dry mouth, confusion, tachycardia |
| Urinary retention | |
| Blockade of H1 histamine receptors | Sedation, weight gain |