Age, disease duration, and disease severity of patients enrolled in this study and the results of comparisons between active stimulation and sham stimulation, and between cerebellar-type SCD and OPCA type SCD receiving active stimulation
| Active | Sham | p Value† | Active cerebellar | Active OPCA | pValue‡ | |
|---|---|---|---|---|---|---|
| Values are shown as mean (SEM). | ||||||
| 10 m time, 10 m steps, Tandem steps are indicated by the same abbreviations used in the text. | ||||||
| *p<0.05 compared with each value before TMS in sham stimulation group; †p Values shown in this table were analyzed between active and sham stimulation groups; ‡p Values shown in this table were analyzed between cerebellar type and OPCA type of active stimulation group. | ||||||
| Age (y) | 56.31 (1.96) | 58.83 (1.47) | 0.32 | 62.00 (2.03) | 54.48 (2.80 | 0.08 |
| Disease durarion (y) | 7.73 (0.71) | 6.67 (0.82) | 0.33 | 8.28 (1.27) | 5.52 (0.91) | 0.10 |
| Disease types (N) (cerebellar:OPCA) | 17:22 | 16:19 | 0.85 | |||
| 10 m time (s): | ||||||
| Before TMS | 14.37 (1.80) | 13.78 (1.23) | 0.79 | 13.74 (2.92) | 16.24 (2.26) | 0.23 |
| After TMS | 9.90 (0.75) | 12.65 (1.20)* | <0.05 | 8.11 (0.49) | 12.16 (1.21) | <0.05 |
| 10 m steps: | ||||||
| Before TMS | 23.88 (2.19) | 25.19 (1.71) | 0.64 | 23.91 (2.22) | 24.41 (3.62) | 0.28 |
| After TMS | 19.47 (1.19) | 23.49 (1.69)* | <0.05 | 19.97 (1.89) | 19.39 (1.55 | 0.40 |
| Tandem steps: | ||||||
| Before TMS | 1.24 (0.37) | 2.26 (0.67) | 0.19 | 2.39 (0.77) | 1.05 (0.49) | 0.20 |
| After TMS | 7.92 (2.12) | 3.25 (1.38) | <0.005 | 10.72 (3.52) | 4.81 (1.87) | <0.05 |
| Standing capacities: | ||||||
| Before TMS | 2.36 (0.18) | 2.43 (0.21) | 0.72 | 2.11 (0.34) | 2.48 (0.18) | 0.17 |
| After TMS | 1.64 (0.11) | 2.11 (0.17)* | <0.05 | 1.23 (0.16) | 1.86 (0.13) | <0.01 |
| Walking capacities: | ||||||
| Before TMS | 2.21 (0.12) | 2.11 (0.20) | 0.64 | 2.00 (0.34) | 2.19 (0.13) | 0.41 |
| After TMS | 1.67 (0.13) | 2.07 (0.20) | 0.09 | 1.23 (0.16) | 1.62 (0.18) | 0.51 |