WML | |||
---|---|---|---|
Characteristic | Present* | Absent | p Value† |
Values are mean (SD) or n. | |||
*WML score >0. | |||
†κ2 test or Student's t test, as appropriate. | |||
‡Symptomatic or asymptomatic lacunar infarcts on MRI. | |||
MRI, magnetic resonance imaging; WML, white matter high intensity lesions on T2 weighted MR images. | |||
Number of patients | 49 | 40 | |
WML | |||
Mild | 40 | ||
Severe | 9 | ||
Lacunar infarction‡ | 30 | 12 | 0.0064 |
Multiple infarction | 18 | 3 | 0.0029 |
Age (years) | 68.4 (8.3) | 63.4 (9.8) | 0.011 |
Sex | |||
Male/female | 25/24 | 13/27 | 0.13 |
Follow up time (months) | 51.1 (21.2) | 51.9 (17.3) | 0.86 |
Other medical illness | |||
Hypertension | 22 | 6 | 0.0052 |
Diabetes mellitus | 13 | 3 | 0.041 |
Ischaemic heart disease | 6 | 2 | 0.41 |
Hypercholesterolaemia | 9 | 4 | 0.42 |
Smoking ever | 9 | 2 | 0.11 |
Current smoking | 6 | 1 | 0.19 |
Past smoking | 3 | 1 | 0.76 |
Antiplatelet treatment | 26 | 13 | 0.09 |