Cardiovascular history and examination: comparison between patients with CIAP, patients with PAD, and controls
| CIAP v controls | PAD v controls | CIAP v PAD | |||||||
|---|---|---|---|---|---|---|---|---|---|
| CIAP (n=97) | PAD (n=97) | Controls (n=96) | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
| Percentages of patients and controls with manifest cardiovascular disease and risk factors are presented. Statistically significant differences are presented in italics. | |||||||||
| CIAP, chronic idiopathic axonal polyneuropathy; PAD, peripheral arterial disease; OR, odds ratio; CI, confidence interval; Fontaine stage I: subclinical PAD; stage II: pain after exercise, stage III: pain in rest, stage IV: ulceration; BMI, body mass index; ABI, ankle brachial index. | |||||||||
| Men/women | 66/31 | 61/36 | 61/35 | ||||||
| Mean(SD) age (years) | 67.5 (7.9) | 67.5 (9.1) | 67.1 (7.3) | ||||||
| Fontaine I/II/III/IV | 12/9/0/0 | 0/80/10/7 | 8/1/0/0 | ||||||
| Cardiovascular risk factors | |||||||||
| Family history positive | 42 | 37 | 21 | 2.8 | 1.5 to 5.2 | 2.2 | 1.2 to 4.3 | 1.2 | 0.7 to 2.2 |
| Hypertension | 56 | 65 | 39 | 2.0 | 1.1 to 3.6 | 3.0 | 1.6 to 5.3 | 0.7 | 0.4 to 1.2 |
| Hypercholesterolaemia | 46 | 60 | 21 | 3.3 | 1.5 to 7.3 | 5.7 | 2.6 to 12.4 | 0.6 | 0.3 to 1.2 |
| Ever smoked | 68 | 92 | 63 | 1.1 | 0.8 to 1.4 | 10 | 3.6 to 25 | 0.1 | 0.04 to 0.3 |
| Current smoking | 38 | 72 | 23 | 2.1 | 1.1 to 3.9 | 8.7 | 4.5 to 16.7 | 0.2 | 0.1 to 0.4 |
| Alcohol use | 70 | 65 | 82 | 0.5 | 0.2 to 0.9 | 0.4 | 0.2 to 0.7 | 1.3 | 0.7 to 2.3 |
| BMI >0.25 | 44 | 45 | 39 | 1.1 | 0.8 to 1.5 | 1.3 | 0.7 to 2.3 | 0.9 | 0.5 to 1.6 |
| Cardiovascular disease | |||||||||
| Stroke | 17 | 18 | 6 | 3.2 | 1.8 to 5.9 | 3.4 | 1.3 to 9.0 | 0.9 | 0.4 to 1.9 |
| Cardiac disease | 28 | 44 | 15 | 2.4 | 1.2 to 4.9 | 4.5 | 2.2 to 9.0 | 0.5 | 0.3 to 1.0 |
| Intermittent claudication | 13 | 92 | 1 | ||||||
| ABI rest <0.9 | 10 | 100 | 1 | 10.8 | 1.4 to 86 | ||||
| ABI after exercise <0.9 | 15 | 100 | 8 | 2.3 | 0.9 to 5.7 | ||||
| Stroke and cardiac disease | 41 | 54 | 19 | 3.0 | 1.6 to 5.8 | 5.0 | 2.6 to 9.9 | 0.6 | 0.3 to 1.1 |