Univariate logistic models for sex, age, apolipoprotein E genotyping, TC, and Lp(a) in AD
| Variable | Coding | Number of subjects | Number of events | Coefficient | SE | Log likelihood | G statistic* | df | p Value | Odds ratio | 95% CI | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| *Likelihood ratio test statistic; †ε3/ε4, and ε4/ε4 genotypes. CI, confidence interval. | ||||||||||||
| Constant | – | – | – | – | – | – | −85.934 | – | – | – | – | – |
| Sex | 0 | Men | 48 | 18 | 0.776 | 0.377 | −83.774 | 4.319 | 1 | 0.04 | 2.17 | 1.04 to 4.55 |
| 1 | Women | 76 | 43 | |||||||||
| Age (years) | 1 | ≤60 | 33 | 11 | 0 | – | −82.994 | 5.880 | – | – | 1 | – |
| 2 | 61–71 | 28 | 13 | 0.550 | 0.529 | 1 | 0.30 | 1.73 | 0.61 to 4.89 | |||
| 3 | 72–76 | 33 | 20 | 1.124 | 0.513 | 1 | 0.03 | 3.08 | 1.13 to 8.41 | |||
| 4 | ≥77 | 30 | 17 | 0.961 | 0.522 | 1 | 0.07 | 2.62 | 0.94 to 7.27 | |||
| Apolipoprotein E ε4 carrier† | 0 | No | 98 | 43 | 1.057 | 0.471 | −83.240 | 5.388 | 1 | 0.03 | 2.88 | 1.14 to 7.25 |
| 1 | Yes | 26 | 18 | |||||||||
| TC (mmol/) | 1 | <4.7 | 31 | 21 | 0 | – | −79.840 | 12.189 | – | – | 1 | – |
| 2 | 4.7–5.3 | 30 | 17 | −0.474 | 0.532 | 1 | 0.37 | 0.62 | 0.22 to 1.77 | |||
| 3 | 5.4–6 | 32 | 15 | −0.867 | 0.523 | 1 | 0.10 | 0.42 | 0.15 to 1.17 | |||
| 4 | >6 | 31 | 8 | −1.798 | 0.562 | 1 | 0.01 | 0.17 | 0.06 to 0.50 | |||
| Lp (a) (mg/l) | 1 | <15 | 31 | 9 | 0 | – | −81.532 | 8.804 | – | – | 1 | – |
| 2 | 15–60 | 32 | 16 | 0.894 | 0.531 | 1 | 0.08 | 2.44 | 0.86 to 6.92 | |||
| 3 | 70–355 | 32 | 21 | 1.540 | 0.543 | 1 | 0.01 | 4.67 | 1.61 to 13.5 | |||
| 4 | ≥360 | 29 | 15 | 0.963 | 0.543 | 1 | 0.09 | 2.62 | 0.90 to 7.59 | |||