Symptoms (%) |
Tingling | 57 | 33 | 17 | 6.5 |
3.3 to 12.8
| 2.5 |
1.2 to 4.9
| 2.7 |
1.5 to 4.8
|
Numbness | 80 | 32 | 16 | 22.2 |
10.5 to 46.7
| 2.5 |
1.2 to 5.1
| 9.0 |
4.5 to 16.7
|
Weakness | 72 | 11 | 11 | 20.0 |
9.3 to 43.2
| 1.0 | 0.4 to 2.4 | 20.4 |
9.4 to 43.5
|
Muscle cramps | 64 | 49 | 31 | 3.9 |
2.1 to 7.1
| 2.1 |
1.1 to 3.7
| 1.9 |
1.1 to 3.3
|
Disability (%) |
Walking distance <1000 m | 21 | 62 | 1 | 24.7 |
3.2 to 188
| 154 |
20.6 to 1153
| 0.2 | 0.1 to 0.3 |
Use of walking aids | 39 | 14 | 4 | 14.8 |
5.0 to 43.7
| 3.9 |
1.2 to 12.3
| 3.8 |
1.9 to 7.7
|
Rankin 0/1/2/3 | 0/31/64/5 | 4/31/60/5 | 69/27/4/0 | | | | | | |
Rankin >1 | 69 | 65 | 4 | 7.2 |
4.1 to 12.4
| 42.6 |
14.4 to 127
| 1.1 | 0.6 to 2.0 |
Signs (%) |
Atrophy hands | 29 | 7 | 7 | 5.2 |
2.1 to 12.5
| 1.0 | 0.3 to 3.0 | 5.2 |
2.2 to 12.6
|
Atrophy lower legs | 54 | 33 | 11 | 8.9 |
4.2 to 18.8
| 3.8 |
1.8 to 8.2
| 2.3 |
1.3 to 4.2
|
Weakness extension feet | 70 | 19 | 1 | 223 |
29.6 to 1675
| 21.9 |
2.9 to 168
| 10.2 |
5.2 to 19.9
|
Ankle jerk absent | 87 | 49 | 35 | 11.8 |
5.7 to 24.2
| 1.7 | 1.0 to 3.1 | 6.9 |
3.4 to 13.9
|
Pin prick sense abnormal | 79 | 38 | 18 | 17.9 |
8.7 to 36.7
| 1.4 | 0.8 to 2.4 | 6.1 |
3.2 to 11.7
|
Touch sense abnormal | 80 | 36 | 19 | 17.9 |
8.7 to 36.4
| 1.3 | 0.8 to 2.1 | 7.2 |
3.7 to 13.7
|
Vibration sense hallux absent | 94 | 41 | 26 | 18.4 |
8.7 to 38.5
| 2.0 |
1.1 to 3.7
| 21.2 |
8.5 to 53.2
|
Neuropathy (%) | 100 | 15 | 5 | | | 3.3 |
1.1 to 10
| | |
Tests (mean (SD)) |
Vibration threshold | 2.0 (2.0) | 1.4 (1.2) | 0.9 (0.8) |
p<0.001
| |
p<0.01
| |
p<0.05
| |
Tapping arm | 29 (8) | 31 (5) | 35 (7) |
p<0.001
| |
p<0.01
| | NS | |
Tapping leg | 29 (11) | 34 (8) | 39 (8) |
p<0.001
| |
p<0.01
| |
p<0.05
| |