Mean (SD) D̅ values of the selected white matter areas from AD patients and controls
| AD | Controls | p Value* | |
|---|---|---|---|
| *Student's t test for non-paired data. | |||
| D̅, mean diffusivity, expressed in units of m2s−1×10−9. Corpus callosum D̅ values were obtained by averaging the values of the splenium and genu of the corpus callosum. Pericallosal D̅ values were obtained by averaging the values of the anterior and posterior pericallosal areas. Internal capsule values were obtained by averaging the values of genu and posterior limb of this structure. | |||
| Corpus callosum | 1.04 (0.10) | 0.86 (0.05) | <0.001 |
| Pericallosal areas | 0.93 (0.1) | 0.84 (0.04) | 0.008 |
| Frontal lobe | 0.93 (0.11) | 0.80 (0.05) | <0.001 |
| Temporal lobe | 1.07 (0.24) | 0.86 (0.06) | 0.003 |
| Parietal lobe | 0.93 (0.10) | 0.82 (0.05) | 0.004 |
| Occipital lobe | 0.93 (0.10) | 0.93 (0.09) | 0.99 |
| Internal capsule | 0.81 (0.07) | 0.81 (0.04) | 0.88 |
| All white matter areas | 0.94 (0.07) | 0.86 (0.03) | <0.001 |