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Biological age less than 70 years
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UPDRS “off” motor score 40–80/108
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Suprathreshold dose levodopa improves score by 50%
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Severe drug induced dyskinesias (pallidal surgery)
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No falls when “on” (pull test)
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MMSE >24/30
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Good bulbar function (particularly in “on” state)
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No significant depression
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No drug induced hallucinosis or other significant psychotic symptoms
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