Risk factors in 26 patients compared with 104 matched controls using multivariate logistic regression analysis
| B (SE) | Multivariate OR (95% CI) | p Value | Univariate OR (95% CI) | |
|---|---|---|---|---|
| *Overall p value for the effect of smoking based on the dosage dependent categories current smokers, previous smokers, and never smokers. | ||||
| Cigarette smoking | 0.76 (0.36) | 2.13 (1.04 to 4.39) | 0.037* | 2.39 (1.27 to 4.49) |
| Never | 0.0 | 1.00 (reference) | 1.00 (reference) | |
| Previous | 0.76 (0.36) | 2.13 (1.04 to 4.39) | 2.39 (1.27 to 4.49) | |
| Current | 1.52 (0.72) | 4.55 (1.08 to 19.30) | 5.71 (1.62 to 20.13) | |
| Coffee consumption (cups/day) | 1.35 (0.67) | 3.86 (1.01 to 14.73) | 0.042 | 4.72 (1.48 to 14.98) |
| ≤5 | 0.0 | 1.00 (reference) | 1.00 (reference) | |
| >5 | 1.35 (0.67) | 3.86 (1.01 to 14.73) | 4.72 (1.48 to 14.98) | |
| Systolic blood pressure | 0.05 (0.01) | 1.04 (1.03 to 1.06) | <0.0001 | 1.02 (1.00 to 1.04) |
| 20 mm Hg increase | 0.90 (0.24) | 2.46 (1.52 to 3.97) | 1.62 (1.17 to 2.22) | |
| Total serum cholesterol (mmol/l) | −0.24 (0.25) | 0.79 (0.48 to 1.29) | NS | 0.89 (0.62 to 1.29) |
| Body mass index (kg/m2) | 0.02 (0.07) | 1.02 (0.89 to 1.18) | NS | 1.00 (0.89 to 1.12) |