Screening procedure and classification schema
| Diagnosis | CERAD14 | Braak16 | Esiri4 |
|---|---|---|---|
| All cases met NINCDS-ADRDA34 clinical criteria for possible or probable AD. Note the lack of overlap between the two groups. The combination of the CERAD and Braak schemes for AD is consistent with current recommendations for the diagnosis of AD.35 | |||
| SVD, Small vessel disease; AD, Alzheimer's disease. | |||
| SVD alone | Normal or possible | Normal (0–2) or limbic (3–4) | SVD (2–3) |
| AD alone | Probable or definite | Neocortical (5–6) | Normal (0–1) |