Case-control studies estimating the frequency of PD among relatives of cases in comparison with controls
| Author | Source of cases | Source of controls | Percentage of cases with family history of disease | Percentage of controls with family history of disease | Familial relative risk (crude) |
|---|---|---|---|---|---|
| Martin 1973 | Clinic series | Case spouses | 26.8 | 14.8 | 1.8 |
| Semchuk 1993 | Clinic series | Age, sex matched community | 22.7 | 6.3 | 3.6 |
| Payami 1994 | Clinic series | Case spouses or friends | 15.8 | 4.0 | 4.0 |
| Vieregge 1995 | Clinic series | Non-neuro hospital patients | 9.1 | 1.4 | 6.5 |
| Bonifati 1995 | Clinic series | Case spouses | 24.0 | 6.0 | 4.0 |
| de Michele 1996 | Clinic series | Spouses and neuro hospital patients | 33.0 | 3.4 | 9.7 |
| Marder 1996 | Population based | Community volunteers | 6.4 | 4.9 | 1.3 |
| Taylor 1999 | Clinic series | Case in-laws or friends | 18.6 | 6.8 | 2.7 |
| Elbaz 1999 | Population based | Community | 10.3 | 3.5 | 2.9 |