Demographics and clinical characteristics of patients according to anticardiolipin (aCL) antibody positivity
| aCL IgG | aCL IgM | |||
|---|---|---|---|---|
| Positive (n=12) | Negative (n=273) | Positive (n=32) | Negative (n=257) | |
| *Progression rate is the ratio of expanded disability status scale (EDSS) score to duration of the disease at sampling time. Data are mean (SD) or number and percentage. PP, primary progressive; RR, relapsing remitting; SP, secondary progressive. | ||||
| Men | 1 (8%) | 85 (31%) | 11 (35%) | 76 (30%) |
| Women | 11 (92%) | 188 (69%) | 21 (65%) | 181 (70%) |
| Age (years) | 44 (12) | 44 (11) | 48 (9) | 43 (11) |
| Age at onset (years) | 30 (10) | 30 (9) | 34 (10) | 29 (9) |
| EDSS | 4 (1.7) | 4.3 (2.2) | 4.9 (1.34) | 4.3 (2.2) |
| Progression rate* | 0.4 (0.3) | 0.4 (0.4) | 0.5 (0.4) | 0.4 (0.4) |
| Course of the disease | ||||
| RR | 7 (59%) | 159 (58%) | 13 (41%) | 155 (60%) |
| SP | 3 (25%) | 68 (25%) | 10 (31%) | 62 (24%) |
| PP | 2 (16%) | 32 (12.5%) | 7 (22%) | 27 (11%) |
| Undetermined | 0 (0%) | 14 (4.5%) | 2 (6%) | 13 (5%) |