Change in HRQOL instrument | |||||
---|---|---|---|---|---|
HRQOL instrument | Regression coefficient† | R2* | Magnitude of change in global ratings | Mean‡ | 95.0% CI |
*R2 assesses the strength of the relation between change in HRQOL instrument and global ratings. | |||||
†The regression coefficients represent the amount of change in HRQOL scores per unit of global rating. | |||||
‡Mean = regression coefficient × magnitude of change in global rating. | |||||
HRQOL, health related quality of life; HUI, health utilities index; MCS, mental composite score of SF-36; MIC, minimum clinically important change; PCS, physical composite score of SF-36; QOLIE, quality of life in epilepsy inventory; SF-36, medical outcomes study short form questionniare. | |||||
QOLIE-89 | 3.38 | 0.45 | Nil | 1.69 | 1.37 to 2.01 |
Small | 8.45 | 6.83 to 10.07 | |||
Medium | 15.21 | 12.29 to 18.13 | |||
Large | 21.97 | 17.75 to 26.19 | |||
MIC | 10.14 | 8.19 to 12.10 | |||
QOLIE-31 | 3.92 | 0.47 | Nil | 1.96 | 1.59 to 2.33 |
Small | 9.80 | 7.96 to 11.64 | |||
Medium | 17.65 | 14.33 to 20.96 | |||
Large | 25.49 | 20.71 to 30.27 | |||
MIC | 11.76 | 9.56 to 13.97 | |||
SF-36 (MCS) | 1.53 | 0.12 | Nil | 0.76 | 0.43 to 1.09 |
Small | 3.82 | 2.17 to 5.47 | |||
Medium | 6.88 | 3.91 to 9.84 | |||
Large | 9.93 | 5.65 to 14.22 | |||
MIC | 4.58 | 2.61 to 6.56 | |||
SF-36 (PCS) | 1.01 | 0.15 | Nil | 0.50 | 0.26 to 0.75 |
Small | 2.51 | 1.29 to 3.73 | |||
Medium | 4.52 | 2.34 to 6.71 | |||
Large | 6.53 | 3.37 to 9.68 | |||
MIC | 3.02 | 1.56 to 4.47 | |||
HUI-III | 0.05 | 0.29 | Nil | 0.03 | 0.02 to 0.03 |
Small | 0.13 | 0.08 to 0.17 | |||
Medium | 0.23 | 0.15 to 0.31 | |||
Large | 0.33 | 0.21 to 0.45 | |||
MIC | 0.15 | 0.1 to 0.21 |