Table 2

Comparison of ventricular volumes in patients who developed clinical MS and McDonald MS versus those who did not develop clinical and McDonald MS

Early MS n=18Asymptomatic n=37Total n=55
Comparing baseline versus one year ventricular volumes *p=0.006,†p=0.402.
Comparing ventricular volume change in MS (n=18) and those with no further symptoms (n=37) ‡p=0.007.
Baseline ventricular volume cm3 median (range)*5.4 (1.2–39.2)†6.0 (1.5–23.1)5.9 (1.2–39.2)
1 year follow up ventricular volume cm3 median (range)*7.7 (1.3–40.6)†6.2 (1.7–24.1)6.3 (1.3–40.6)
‡Ventricular volume change cm3 median (range)+0.5 (−0.6–7.2)+0.06 (−0.9–1.4)+0.1 (−0.9–7.2)
McDonald MS n=27McDonald MS negative n=28
Comparing baseline versus one year ventricular volumes *p=0.005, †p=0.632. Comparing ventricular volume change in patients with McDonald MRI MS (n=27) and those without (n=28) ‡p=0.03.
Baseline ventricular volume cm3 median (range)*6.0 (1.2–39.2)†5.3 (1.7–23.1)
1 year follow up ventricular volume cm3 median (range)*8.1 (1.4–40.6)†5.2 (1.7–24.1)
‡Ventricular volume change cm3 median (range)+0.3 (−0.7–7.2)+0.05 (−0.9–1.4)