Table 4

Ventricular volumes in patients with normal and abnormal T2 weighted MRI (that is, ≥1 T2 lesion) at baseline. Ventricular volumes in patients with abnormal baseline T2 weighted MRI: comparison of those with and without gadolinium (Gd) enhancing and T1 hypointense lesions

Normal and abnormal baseline MRI (n=55)Abnormal baseline MRI (n=40)
Normal MRI (n=15)Abnormal MRI (n=40)Gd lesions (n=15)No Gd lesions (n=25)T1 hypointense lesions (n=21)No T1 hypointense lesions (n=19)
Baseline ventricular volume cm3 median (range)4.3 (2.6–23.1)6.4 (1.2–39.2)7.9 (3.1–25.9)5.9 (1.2–39.2)6 (1.2–25.9)6.9 (1.7–39.2)
One year ventricular volume cm3 median (range)4.4 (2.4–24.1)6.8 (1.4–40.6)10.3 (3.2–26.5)6.5 (1.4–40.6)6.7 (1.4–26.5)7 (1.7–40.6)
Ventricular volume change cm3 median (range)−0.2 (−0.9–1.0)0.2 (−0.7–7.2)+0.7 (−0.6–7.2)+0.1 (−0.7–1.6)+0.5 (−0.6–7.2)+0.03 (−0.7–1.9)
Comparing baseline and one year ventricular volumesp=0.46P=0.001p=0.004p=0.069p=0.001p=0.376