Table 5

Correlation of change in ventricular volume over one year with other MRI lesion measures and with EDSS

Correlationr Valuep Value
*Significant correlations using Bonferroni correction p<0.003.
Baseline T2 lesion number0.3390.011
Baseline T2 lesion volume0.3810.004
Change in T2 lesion volume over one year0.2020.138
Sum of baseline and new T2 lesion numbers at one year0.3860.006
Number of new T2 lesions at month 12 compared with baseline0.2540.061
1 year T2 lesion volume0.4470.001*
Baseline Gd lesion number0.3540.008
Month 3 Gd lesion number0.3670.007
Baseline and month 3 Gd lesion number0.380.006
Month 12 Gd lesion number0.2060.132
Baseline, month 3 and month 12 Gd lesion number0.3850.005
Baseline T1 hypointense lesion number0.495<0.001*
Baseline T1 hypointese lesion volume0.467<0.001*
Change in T1 hypointense lesion volume over one year0.050.735
One year T1 hypointense lesion volume0.4210.001*
Baseline EDSS0.1320.335
EDSS at month 120.3170.019
EDSS change over one year0.1160.398