Statistical analysis of outcome in functional tests after shunt operation compared with baseline in patients positive for lumbar infusion and CSF tap tests
| LIT positive (n=40) | TT positive (n=17) | LIT and TT positive (n=10) | LIT positive/TT negative (n=30) | LIT negative/TT positive (n=7) | ||
|---|---|---|---|---|---|---|
| Values are mean (SD). | ||||||
| *p < 0.05; **p < 0.01; ***p < 0.001 v baseline (Wilcoxon matched pairs signed ranks test); no other difference significant. | ||||||
| 1Baseline values refer to the best of two results. | ||||||
| 2One patient was unable to walk and one was unable to walk or to perform the reaction time test at baseline, but both were fully able to perform at follow up. Two patients did not manage the reaction time test at follow up. These patients were all excluded from the statistical analyses of those particular tests. | ||||||
| LIT, lumbar infusion test; TT, cerebrospinal fluid tap test. | ||||||
| Walking test (number of steps) | Baseline1 | 48 (29)2 | 44 (21) | 47 (21) | 49 (32)2 | 40 (24) |
| Follow up | 41 (33)*** | 36 (19) | 37 (20) | 42 (37)*** | 34 (18) | |
| Walking test (time) (s) | Baseline | 29 (24)2 | 26 (14) | 26 (11) | 31 (27)2 | 27 (19) |
| Follow up | 25 (27)*** | 22 (16) | 22 (18) | 26 (30)*** | 21 (14) | |
| Memory (number of correct answers) | Baseline | 3.7 (1.8) | 3.7 (1.9) | 3.8 (1.7) | 3.6 (1.9) | 3.6 (2.2) |
| Follow up | 4.4 (2.1)*** | 4.6 (1.3)* | 4.9 (1.5)** | 4.2 (2.3)** | 4.1 (1.1) | |
| Reaction time (ms) | Baseline | 377 (218)2 | 506 (443) | 374 (175) | 378 (235)2 | 693 (639) |
| Follow up | 298 (151)** | 351 (205)** | 294 (97)* | 300 (168)* | 433 (290) | |
| Identical forms test (number of correct answers) | Baseline | 19.3 (12.3) | 17.1 (12.0) | 17.6 (11.0) | 19.8 (12.8) | 16.5 (14.0) |
| Follow up | 20.3 (12.4) | 23.6 (13.0)** | 23.6 (7.4) | 19.2 (13.5) | 24.0 (19.0) | |