Comparison of each variable in patients with Parkinson’s disease and control subjects
| At rest | Tilt up | CVRR (%) | Noradrenaline (ng/ml) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | MBP | MSNA | ΔHR | ΔMBP | ΔMSNA | Supine | Standing | ||
| Values are mean (SD). | |||||||||
| *p<0.05 v controls. | |||||||||
| CVRR, coefficient of RR interval variability on ECG (standard deviation × mean RR interval−1×100); HR, heart rate (beats/min); MBP, mean blood pressure (mm Hg); MSNA, muscle sympathetic nerve activity (bursts/100 heart beats). | |||||||||
| Control (n=21) | 74.5 (9.0) | 88.2 (16.0) | 64.2 (15.5) | 4.4 (2.7) | 14.5 (7.6) | 8.7 (4.1) | 7.0 (1.3) | 0.26 (0.14) | 0.49 (0.18) |
| Parkinson’s disease (n=14–18) | 76.8 (10.5) | 93.7 (15.9) | 58.3 (12.4) | 3.4 (2.0) | 5.7 (8.7)* | 7.6 (3.3) | 5.9 (2.0) | 0.23 (0.11) | 0.32 (0.13)* |